Case Study

DecisionDx Squamous Cell Carcinoma

Can this patient avoid further treatment?

A 72-year-old Caucasian male presents with primary SCC of the central forehead.

Case details

The patient's lesion, located on his forehead, was 2.8 x 1.5 cm. The patient has type 2 diabetes, hypertension, renal cell carcinoma s/p right nephrectomy.

  • Post-operative adjuvant radiation therapy. 

Why DecisionDx-SCC?

Post-operative radiation therapy considered due to the high-risk features of large size and tumor depth> 4 mm. The patient wished to avoid further treatment if possible. 

Test result

In this patient, the DecisionDx-SCC test result of Class 2A indicates a higher biological risk for metastasis (38.6%). This assisted the clinician in deciding to proceed with the treatment pathway – ART treatment 5 months post-initial surgery to decrease chance of recurrence or metastasis. 


The DecisionDx-SCC test result of Class 2A indicates a higher biological risk for metastasis (38.6%). This assisted the clinician in deciding to proceed with the treatment pathway – ART treatment 5 months post-initial surgery to decrease chance of recurrence or metastasis. 

DecisionDx-SCC testing provided valuable objective information and helped determined that the patient should proceed with the ART treatment.

 This case study was published by Singh et al. Clinical, Cosmetic and Investigational Dermatology 2023 
1. Wysong et al. Late breaking presentation at AAD 2023; Data on file, Castle Biosciences